tumor microenvironment

Researchers connect a tumor’s leading edge transcriptional profile to poor survival outcomes across cancer types. 

Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.

Free-swimming bacteria settle on a surface to cooperate and form a protective biofilm.

Colonizing tumors with engineered bacteria may allow researchers to target sites currently inaccessible to radionuclide therapy.

The University of Chicago cell biologist is studying how the nutrients available to cancers influence their growth. 

Research into how pancreatic tumors adapt to stress could lead to a new treatment approach.

Human and mouse oral tumors recruit nerves to produce peptides that the cancer cells need to survive—but this process can be blocked with a migraine drug.

Most differences in gene expression among cells within a tumor are likely due to environment or noise, a study suggests. 

Whether the finding of a novel mechanism for cancer-related pain can lead to better treatments for neuropathic pain in people remains to be seen.

Starving glioblastoma tumors of the cholesterol made by astrocytes could suppress brain cancer progression.

Scientists discover tumor-associated T cells that drive breast cancer metastasis to lymph nodes.

At Brigham and Women’s Hospital, the cancer biologist is combining research into the tumor microenvironment with the principles of neuroscience to tease apart how cancers grow—and how to stop them.

Because most people are vaccinated against tetanus as children, delivering benign bacteria carrying a tetanus antigen into pancreatic tumors makes them visible to memory cells in the immune system, researchers report.