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Composition of DNA with a glitch effect
“Silent” Mutations Make Noise In Cancer
Synonymous mutations have long been ignored in cancer studies since they don’t affect the amino acid sequences of proteins. But research increasingly reveals that they can have disease-driving effects.
“Silent” Mutations Make Noise In Cancer
“Silent” Mutations Make Noise In Cancer

Synonymous mutations have long been ignored in cancer studies since they don’t affect the amino acid sequences of proteins. But research increasingly reveals that they can have disease-driving effects.

Synonymous mutations have long been ignored in cancer studies since they don’t affect the amino acid sequences of proteins. But research increasingly reveals that they can have disease-driving effects.

synonymous mutation

synonymous mutation bap1 kidney cancer clear-cell renal cell carcinoma
“Silent” Mutation Linked to Worse Kidney Cancer Outcome
Katarina Zimmer | Feb 17, 2021 | 6 min read
A synonymous mutation in the tumor suppressor gene BAP1 can result in loss of function of the protein without altering its amino acid sequence.
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