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Finally, Scientists Sequence Single Cells with Long-Read Technology
Finally, Scientists Sequence Single Cells with Long-Read Technology
By combining two innovative approaches, researchers can now sequence the full spectrum of mutational differences between individual cells’ genomes.
By combining two innovative approaches, researchers can now sequence the full spectrum of mutational differences between individual cells’ genomes.
single cell
The Cellular Intricacies of the Human Placenta
Ida Emilie Steinmark, PhD | Jul 5, 2023 | 2 min read
Rare samples saved 35 years ago helped researchers map gene expression and cell differentiation in first trimester placentas.
2022 Top 10 Innovations
The Scientist Staff | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Accelerating Antibody Discovery for Difficult Targets
The Scientist’s Creative Services Team | 1 min read
François Romagné will discuss how RNA immunization and single cell screening enhance antibody generation for poorly immunogenic proteins.
Cancer-like Slime Mold Growth Hints at Multicellularity’s Origins
Natalia Mesa, PhD | Apr 4, 2022 | 4 min read
The poorly understood Fonticula alba, a relative of fungi and animals, hunts bacteria with a mechanism that resembles cancer and fungal growth.
Stem Cells in Human Teeth Follow the Rules of Their Environment
Roni Dengler, PhD | Feb 7, 2022 | 2 min read
How stem cells in human teeth respond to different environmental conditions offers clues for regenerative medicine.
Best Practices for Single-Cell Proteomics Using Mass Spectrometry
The Scientist’s Creative Services Team | 1 min read
In this webinar, Runsheng Zheng and Fernanda Salvato will discuss how to optimally examine single-cell proteomes through label-free, data-independent acquisition (DIA) mass spectrometry.
Our Favorite Cell and Molecular Biology Stories of 2021
Jef Akst | Dec 2, 2021 | 3 min read
Beyond The Scientist’s coverage of COVID-19’s molecular underpinnings were many other stories highlighting the advances made in scientists’ understanding of the biology of cells.
Experts Predict the Hottest Life Science Tech in 2021 and Beyond
Bob Grant | Feb 1, 2021 | 7 min read
Last year’s Top 10 Innovations judges look into their crystal balls.
Single Cell Sequencing in a Nutshell
Niki Spahich, PhD | 4 min read
By exploring the inner workings of individual cells, rather than averaging bulk populations, researchers identify rare and important cell subtypes.
The Advances that Will Shape Life Sciences in the 2020s
Emma Yasinski | Jan 3, 2020 | 3 min read
Systems biologist Steven Wiley says advancements in two areas—single-cell biology and CRISPR—are poised to transform research.
Image of the Day: Expressive Hydra
Nicoletta Lanese | Jul 26, 2019 | 1 min read
Researchers track which genes are active in the polyp during successive cell states.
Understanding How Single Cell Evolution Drives Tumor Complexity
The Scientist’s Creative Services Team | 1 min read
Andris Abramenkovs and Mark Lynch will discuss how to overcome challenges obtaining high-definition genomic data from single cells.
Revealed: New Cortical Neuron Types
Ashley P. Taylor | Oct 31, 2018 | 2 min read
A pair of mouse studies describes neuronal subpopulations not identified before and some of their functions.
Here Comes Single-Cell Optogenetics
Ruth Williams | Mar 1, 2018 | 3 min read
A new protein may allow researchers to home in on individual neurons, determining their activity minute by minute.
A Guide to Mapping the Complexity of the Tumor Microenvironment
The Scientist’s Creative Services Team | 1 min read
High-quality sample preparation, single-cell analysis, and ultra-high content spatial proteomics for multi-dimensional research workflows.
Image of the Day: Itty Bitty Cell Sucker
The Scientist Staff | Jul 21, 2017 | 1 min read
With a diameter smaller than 100 nanometers, this nanopipette’s indiscernible tip is tiny enough to suck up minute contents of a single cell.
Image of the Day: Sharp Shooters
The Scientist Staff | Apr 3, 2017 | 1 min read
Single-celled dinoflagellates (Polykrikos) use harpoon-like organelles to hunt and capture prey.
Single Cell Resolution Reveals Cellular Diversity
The Scientist’s Creative Services Team and 10x Genomics | 1 min read
Access to single cell resolution reveals new insights into how the human body and its cells operate during health and disease.
Gene Expression in a Drop
Ruth Williams | Aug 1, 2015 | 3 min read
Tens of thousands of individual cells can have their transcriptomes analyzed simultaneously thanks to two new techniques.