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3D rendered medical illustration of T cells trying to subdue cancer cells.
How Tumors Tire Out T Cells
Researchers investigated how cancer antigenicity drives unique forms of T cell exhaustion and hypofunctionality.
How Tumors Tire Out T Cells
How Tumors Tire Out T Cells

Researchers investigated how cancer antigenicity drives unique forms of T cell exhaustion and hypofunctionality.

Researchers investigated how cancer antigenicity drives unique forms of T cell exhaustion and hypofunctionality.

single-cell analysis

Cancer cell
Interrogating the Complexities of the Tumor Microenvironment
Alison Halliday, PhD, Technology Networks | May 19, 2023 | 5 min read
Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist Staff | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Learn about rapid cell screening for antibody therapeutic discovery
The Future of Antibody Discovery for Biotherapeutics
Sartorius | 1 min read
Modern screening methods help usher in a new age of antibody therapeutics. 
Logo for The Scientist's 2022 Top 10 Innovations
Last Chance to Enter Our Annual Top 10 Innovations Contest
The Scientist Staff | Jul 11, 2022 | 1 min read
There is only one week remaining to submit your new product to vie for a coveted spot in The Scientist’s 2022 competition.
Muscle immobilization leads to atrophy
Antioxidants Put the Pep Back in One’s Step
Niki Spahich, PhD | Jun 13, 2022 | 3 min read
Delivering antioxidants via extracellular vesicles to atrophied muscles restores them during rehabilitation.
Optimizing Reproducibility in Flow Cytometry
Beckman Coulter Life Sciences | 1 min read
Explore real solutions for single cell research.
ace2 tmprss2 coronavirus sars-cov-2 covid-19 single-cell sequencing transcript genetic
Receptors for SARS-CoV-2 Present in Wide Variety of Human Cells
Chris Baraniuk | Apr 29, 2020 | 4 min read
Analyses from single-cell sequencing datasets support the idea that COVID-19 is not just a respiratory disease but an illness that can affect multiple organs.
an illustration of a single cell with a backdrop of similar cells
The Advances that Will Shape Life Sciences in the 2020s
Emma Yasinski | Jan 3, 2020 | 3 min read
Systems biologist Steven Wiley says advancements in two areas—single-cell biology and CRISPR—are poised to transform research.  
Discover Strategies for Simultaneous Protein and RNA Single Cell Analysis
Get the Most Out of Single Cells with Multiomic Cytometry
The Scientist’s Creative Services Team and 10x Genomics | 1 min read
Researchers optimize technologies to simultaneously obtain proteomic and transcriptomic data from single cells.
Worm Embryogenesis: Cell by Cell and Gene by Gene
Kerry Grens | Dec 1, 2019 | 2 min read
A single-cell map of C. elegans’s transcriptome during development finds cell lineages that start out genetically different and end up as cells of similar function and genetic profile.
Hydra single-cell sequencing gene expression
Image of the Day: Expressive Hydra
Nicoletta Lanese | Jul 26, 2019 | 1 min read
Researchers track which genes are active in the polyp during successive cell states.
39923-ts-capturing-heterogeneity-webinar-banner-jp800x560
Capturing Heterogeneity: How Single Cell Analysis Reshapes Health and Disease Research
The Scientist’s Creative Services Team | 1 min read
Timothy O’Sullivan and Jacob Blum will discuss how they use single cell data to understand complex biological systems.
Neural Cell Types Tied to Autism Identified in Single-Cell Study
Ruth Williams | May 16, 2019 | 3 min read
An RNA analysis of human brain cells reveals gene expression changes in cortical neurons and microglia linked to autism spectrum disorder (ASD).
Hindsight
Bob Grant | Dec 1, 2018 | 2 min read
Looking back at a year filled with discoveries and challenges.
LabTalk Podcast - Predicting the Immune Response with Single-Cell Analysis: Autoimmunity, Vaccination, and COVID-19
The Scientist’s Creative Services Team and 10x Genomics | 1 min read
Researchers identify signatures that predict how a person will respond to an immune system stimulus.
2018 Top 10 Innovations
The Scientist Staff | Dec 1, 2018 | 10+ min read
Biology happens on many levels, from ecosystems to electron transport chains. These tools may help spur discoveries at all of life's scales.
Revealed: New Cortical Neuron Types
Ashley P. Taylor | Oct 31, 2018 | 2 min read
A pair of mouse studies describes neuronal subpopulations not identified before and some of their functions.
The Scientist's LabTalk Podcast - Episode 2
The Scientist’s Creative Services Team | 1 min read
Surviving Stress: The mysteries of neuronal survival and neurodegeneration
Image of the Day: Transgenic Axolotl
Kerry Grens | Oct 3, 2018 | 1 min read
Lineage tracing reveals how cells help the salamanders regrow chopped-off limbs.
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