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Illustration of myelinated neuron axons in light blue, with spindly blue and purple cells interspersed among them.
A Gene Variant Linked to Alzheimer’s May Disrupt Myelin Production
The APOE4 variant causes cholesterol buildup in the cells that make protective fatty sheaths for neurons, possibly helping explain its role in neurodegeneration.
A Gene Variant Linked to Alzheimer’s May Disrupt Myelin Production
A Gene Variant Linked to Alzheimer’s May Disrupt Myelin Production

The APOE4 variant causes cholesterol buildup in the cells that make protective fatty sheaths for neurons, possibly helping explain its role in neurodegeneration.

The APOE4 variant causes cholesterol buildup in the cells that make protective fatty sheaths for neurons, possibly helping explain its role in neurodegeneration.

oligodendrocyte progenitor cells

?Sci Philo
Starting with Human Cell Systems 
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Xitiz Chamling shares how advances in human stem cell and gene editing technologies fuel his drive for better multiple sclerosis drug screening platforms.
Microscopy image of a fluorescent green oligodendrocyte surrounded by astrocytes stained red with blue nuclei.
Searching for a Direct Route to Multiple Sclerosis Treatment
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Researchers created a new high-throughput tool to hunt for therapies that remyelinate the nervous system.
A colorized transmission electron microscope image of an oligodendrocyte (blue) surrounded by cells that it coated in myelin (red outlines).
Brain Fluid from Youngsters Gives Old Mice a Memory Boost
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Two oligodendrocyte progenitor cells are being generated from adult stem cells nestled on the surface of brain ventricle
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Amanda Heidt | Jun 10, 2021 | 5 min read
A pool of neural stem cells that ordinarily lies dormant in the brains of adult mice spawns two types of never-before-documented glial cells when artificially reactivated, potentially pointing to a novel mechanism of brain plasticity.
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