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A graph showing how scGPT groups cells, each represented as a dot, into cell types, shown as clusters of dots of the same color.
A New AI Tool Predicts Gene Expression in a Single Cell
An artificial intelligence tool, scGPT, can identify cell types, predict the effects of disrupting genes, and pinpoint which genes interact with each other.
A New AI Tool Predicts Gene Expression in a Single Cell
A New AI Tool Predicts Gene Expression in a Single Cell

An artificial intelligence tool, scGPT, can identify cell types, predict the effects of disrupting genes, and pinpoint which genes interact with each other.

An artificial intelligence tool, scGPT, can identify cell types, predict the effects of disrupting genes, and pinpoint which genes interact with each other.

News & Opinion

Blood vessel with flowing red blood cells and white immune cells.
New CRISPR Treatment Could Prevent HIV Reinfection after Viral DNA Excision
Jennifer Zieba, PhD | Aug 21, 2023 | 3 min read
Researchers design dual CRISPR treatments to remove HIV DNA and prevent reinfection in vitro.
Six black-and-white MRI images of a brain at different cross-sections.
Is DIANA fMRI Data Real?
Ida Emilie Steinmark, PhD | Aug 17, 2023 | 4 min read
New preprints failed to reproduce the buzzy new neuroimaging technique DIANA fMRI, but its inventor remains steadfast.
A transverse section of stem wood from the researchers’ greenhouse-grown poplar tree.
CRISPR Trees Could Improve Paper Production
Alejandra Manjarrez, PhD | Aug 15, 2023 | 3 min read
Researchers edited several tree genes to improve suitability and sustainability in the pulp and paper industry.
A drawing of the sun on the sand, surrounded by items that people use to protect themselves from UV damage, including sunscreen, a hat, and sunglasses.
Taking Snapshots of DNA Damage in Skin Cancer
Deanna MacNeil, PhD | Aug 15, 2023 | 3 min read
Researchers turn to high resolution sequencing to explain recurrent melanoma mutations caused by UV exposure.
Caenorhabditis elegans, a free-living transparent nematode (roundworm), about 1 mm in length.
The Body, Not the Brain, Regulates Sleep
Rebecca Roberts, PhD | Aug 15, 2023 | 3 min read
Genetic screens have revealed three peripheral tissue genes that regulate sleep. What does this mean for sleep research?
Professor Alexandra Whiteley and graduate student Autumn Matthews look at an image of a western blot on their laboratory computer.
An Ancient Viral Protein May Play a Key Role in ALS
Aditi Subramaniam, PhD | Aug 15, 2023 | 4 min read
Researchers find that UBQLN2 gene dysfunction causes a virus-like protein to accumulate in cells, which changes gene expression and may contribute to disease progression in amyotrophic lateral sclerosis (ALS).
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Surreal illustration of the mind, represented by a person-shaped iceberg. A scuba diver illuminates the dark side of the iceberg underwater with a flashlight.
Toward Better Biomarkers for Schizophrenia
Deanna MacNeil, PhD | Aug 7, 2023 | 3 min read
Researchers scratch the surface of schizophrenia susceptibility by uncovering DNA methylation differences in neonatal blood samples.
Medical illustration of brain cancer with a microscopic magnification of malignant cells dividing in the tumor microenvironment.
Capturing the Brain Tumor Microenvironment with Tissue Engineering
Deanna MacNeil, PhD | Aug 4, 2023 | 3 min read
Researchers built a 3D glioblastoma model to study therapeutic resistance and improve drug screening systems.
Conceptual image of hair loss showing trees in the shape of a human head at various seasonal stages of shedding their leaves.
Islands of Knowledge: Hairy Skin Moles Make Their Mark
Iris Kulbatski, PhD | Aug 7, 2023 | 3 min read
Skin moles that sprout thick, long hairs produce signaling molecules that stimulate hair follicle stem cells to initiate new hair growth. This discovery may make baldness a thing of the past.
Dendritic Cell activate T cells, trigger immune responses, they are responsible of cells protection of the body.
Circadian Signaling Affects T Cell Responses to Vaccination
Nathan Ni, PhD | Aug 9, 2023 | 3 min read
Annie Curtis’s research team revealed how circadian rhythm-regulated mitochondrial metabolism drives dendritic cell antigen presentation activity.
Doctor in rubber gloves wiping injection site on arm of little girl before vaccination
Vaginal Delivery Promotes Early Childhood Vaccine Response
Jennifer Zieba, PhD | Aug 8, 2023 | 3 min read
Researchers showed that the delivery method affects the microbiome and plays a role in the infant vaccine immune response.
Human finger touching a conceptual image of a brain, triggering an electrical spark.
Shaping Brain Recovery Using Bioelectricity
Iris Kulbatski, PhD | Aug 4, 2023 | 3 min read
Scientists are decoding how electrically stimulating transplanted stem cells helps heal the injured brain.
Harvesting cells with a cell scraper

Inducing Cardiomyocyte Maturation

Jennifer Zieba, PhD | Aug 1, 2023 | 2 min read
By combining calcium and electrical pacing, researchers designed a scalable protocol for culturing mature cardiac tissues from induced pluripotent stem cells.
ConPlex predicts what proteins a drug is likely to bind, which can help identify new targets for existing drugs.
Simplifying the Search for Drug Targets
Aparna Nathan, PhD | Aug 1, 2023 | 3 min read
A new machine learning model promises fast prediction of drug-target interactions.
An older woman wearing a blue suit, shaking hands with an older man wearing a black suit.
Iconic Geneticist Evelyn Witkin Dies at Age 102
Lisa Winter | Jul 24, 2023 | 3 min read
Lasker Award winner Evelyn Witkin discovered the mechanism for DNA repair following UV damage.
iStock
Death by Stem Cell: Developing New Cancer Therapies
Charlene Lancaster, PhD | Jul 24, 2023 | 3 min read
Khalid Shah engineers stem cells to deliver cancer therapeutics directly to tumors, thereby increasing their efficacy.
Glass mosaic with the image of two people. The bodies are arbitrarily crossed by lines that divide them into amorphous fractions, some of them colored.
Noninherited Genetic Mutations Link to Schizophrenia
Alejandra Manjarrez, PhD | Jul 20, 2023 | 2 min read
By studying the genomes of more than 24,000 individuals, researchers discovered rare genetic mutations that may shed light on mechanisms underlying schizophrenia.
Close-up of women’s hands using lancet on finger.
A Noninvasive Glucose Monitor for Managing Diabetes
Natalia Mesa, PhD | Jul 20, 2023 | 3 min read
A new, invisible fluorescent patch continuously monitors blood glucose levels in mice.
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