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Lipid nanoparticle
Which Gene Therapy Delivery Vector Will Emerge Victorious? 
In the race to deliver successful gene therapies, frontrunner AAVs come head to head with underdog lipid nanoparticles. 
Which Gene Therapy Delivery Vector Will Emerge Victorious? 
Which Gene Therapy Delivery Vector Will Emerge Victorious? 

In the race to deliver successful gene therapies, frontrunner AAVs come head to head with underdog lipid nanoparticles. 

In the race to deliver successful gene therapies, frontrunner AAVs come head to head with underdog lipid nanoparticles. 

nanoparticle

SARS-CoV-2 self-assembling virus-like nanoparticle with spike proteins protruding from the surface.
New Technology Improves SARS-CoV-2 mRNA Vaccine-Induced Immune Responses
Elina Kadriu | May 30, 2023 | 3 min read
mRNA-encoded self-assembling enveloped virus-like particles presenting SARS-CoV-2 spike protein enhance immunity and may provide better protection against viral variants. 
Lipid nanoparticle delivers treatment to a cancer cell.
Researchers Develop a CRISPR-Based Therapy That Penetrates Solid Tumors
Jennifer Zieba, PhD | Oct 10, 2022 | 3 min read
By packaging lipid nanoparticles with elements that decrease the fibrous nature of solid tumors, researchers can deliver CRISPR therapies in a more efficient manner.
Discover How to Design Sensitive Nucleic Acid Lateral Flow Assays
Go with the Flow: Adapting Lateral Flow Assays for Nucleic Acid Detection
The Scientist’s Creative Services Team and nanoComposix | 1 min read
Scientists incorporate sensitive nanoparticles to rapidly detect DNA and RNA.
Salmonella (pink) invading a human epithelial cell (yellow)
Modified Salmonella Revs Immune Response, Combats Tumors in Mice
Natalia Mesa, PhD | Feb 3, 2022 | 5 min read
When coated with positively charged particles, the bacteria shuttled antigens out of tumors and activated the immune system, a study finds.
neutrobots, neutrophils, white blood cells, microrobots, nanorobots, microbots, glioma, brain cancer, paclitaxel, magnetic, swarm, mice
Microscopic Robots Deliver Drugs to the Brain
Asher Jones | Mar 30, 2021 | 5 min read
Researchers turned white blood cells called neutrophils into drug-smuggling “neutrobots,” which penetrated the blood-brain barrier to treat brain cancer in mice.
An immunoglobulin, also known as an antibody, floating in solution.
Shining a Light on Mass Photometry
The Scientist’s Creative Services Team and Refeyn | 3 min read
Mass photometry is an interferometric scattering-based technique offering researchers unprecedented characterization of biomolecular complexes and oligomerization in physiologically-relevant situations.
Infographic: Building Bacteria to Fight Cancer
Simone Schuerle and Tal Danino | Apr 1, 2020 | 3 min read
Researchers are engineering microbes to deliver therapeutics specifically to tumors, maximizing the treatments’ efficacy while minimizing side effects.
Bacteria as Living Microrobots to Fight Cancer
Simone Schuerle and Tal Danino | Apr 1, 2020 | 10+ min read
Autonomous, living microrobots that seek and destroy cancer are not as futuristic as one might imagine, thanks to a fusion of robotics and synthetic biology.
Exosomes, microvesicles, and apoptotic bodies: The three major types of extracellular vesicle.
Extracellular Vesicles: Applications and Potential
Beckman Coulter Life Sciences | 1 min read
Explore why extracellular vesicles are attractive candidates for new therapeutic approaches.
Air Pollution Tied to Brain Cancer: Study
Emily Makowski | Nov 13, 2019 | 2 min read
Inhaling combustion-produced particles may lead to the development of brain tumors.
Light-Activated Nanodevices Control Cells
Ruth Williams | Sep 1, 2019 | 3 min read
DNA-coated gold nanorods enable cells to be activated by light without genetic manipulation.
gold nanoshells
Getting More Lateral Flow Test Sensitivity with Nanoshell Probes
The Scientist’s Creative Services Team and nanoComposix | 3 min read
Silica-gold nanoshells highlight how good probe design can boost assay performance.
Infographic: Optogenetics Without Genetic Engineering
Ruth Williams | Sep 1, 2019 | 1 min read
DNA-loaded nanoparticles that respond to infrared light provide an alternative way to control cell behavior.
Nanoparticles Let Mice See Near Infrared Light
Abby Olena, PhD | Feb 28, 2019 | 4 min read
Researchers injected the retinas of mice with nanoparticles that bound to photoreceptors and converted near-infrared light to green light that the animals could see.
literature
Molecules Found in Ginger Remodel the Microbiome
Katarina Zimmer | Feb 1, 2019 | 3 min read
Small RNA-containing particles in ginger root are found to promote the growth of beneficial bacteria and alleviate colitis in mouse guts.
literature infographic
Infographic: How Ginger Remodels the Microbiome
Katarina Zimmer | Feb 1, 2019 | 1 min read
Small microRNA-containing particles found in the plant can boost populations of healthy gut bacteria, and even improve colitis symptoms in mice.
How to Track Metabolites in Tissues Using NMR
Katherine Bourzac | Aug 1, 2018 | 7 min read
Whether it’s aligning software or prepping samples, researchers share their tips for studying the metabolome with this underused approach.
Nonviral CRISPR Delivery a Success
Abby Olena, PhD | Oct 2, 2017 | 3 min read
Researchers use gold nanoparticles to deliver CRISPR-Cas9 and correct a point mutation in a mouse model of Duchenne muscular dystrophy. 
Tattoo Ink Nanoparticles Persist in Lymph Nodes
Jef Akst | Sep 12, 2017 | 2 min read
Analysis of the bodies of deceased individuals can’t determine what effect these tattoo remnants have on lymph function, but researchers suggest dirty needles aren’t the only risk of the age-old practice.
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