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Improve CAR T cell sorting to enhance safety and clinical outcomes
A Better Way to Isolate CAR T Cells 
Scientists isolate rare yet desirable CAR T cell subtypes using an innovative cell sorter system within a closed manufacturing process.
A Better Way to Isolate CAR T Cells 
A Better Way to Isolate CAR T Cells 

Scientists isolate rare yet desirable CAR T cell subtypes using an innovative cell sorter system within a closed manufacturing process.

Scientists isolate rare yet desirable CAR T cell subtypes using an innovative cell sorter system within a closed manufacturing process.

lymphocytes

Editing genome stock photo
Resolving Discrepancies in Mouse and Human Autoimmunity Studies
Niki Spahich, PhD | May 15, 2023 | 4 min read
By editing primary T cells with CRISPR, researchers begin to settle a long-standing debate about a common autoimmunity risk variant.
3D medical illustration of peripheral blood cells: a lymphocyte (left) and a monocyte (right) surrounded by red blood cells.
PBMCs: Mononucleated and Multipurposed
Deanna MacNeil, PhD | Dec 16, 2022 | 4 min read
Researchers employ peripheral blood mononuclear cells (PBMCs) in clinical and academic applications related to the immune system and regenerative medicine.
a small black mouse sits next to an obese black mouse on a white background
Obesity Protects Against Genital Herpes in Mice, Study Finds
Katherine Irving | Nov 11, 2022 | 3 min read
A high-fat diet induced changes to the animals’ vaginal microbiomes that boosted survival after exposure to the virus.
Curiox
Improving Tumor-Infiltration Lymphocyte (TIL) Extraction
Curiox | May 17, 2022 | 1 min read
Discover a better method for consistent TIL isolation and characterization from tumor samples.
Artist’s rendering of multiple natural killer cells, colored light pink, attacking a purple tumor cell.
Protein Pilfered from Cancer Cells Thwarts Immune Attack
Dan Robitzski | Apr 13, 2022 | 3 min read
New research in mice reveals why natural killer cells, normally effective at hunting cancer, are sometimes stopped in their tracks.  
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Training Immune Cells to Be Cancer Killers
Aparna Nathan, PhD | Nov 12, 2021 | 4 min read
A career-altering experience as a cancer patient motivated one researcher to design more potent immunotherapies.
Excess of Immune Cells Found in Brains of People with Autism
Ashley Yeager | Jan 13, 2020 | 5 min read
An accumulation of T cells and astrocytes in postmortem brain tissue hints at possible autoimmune origins for many cases of autism.
x lymphocyte DE cell immune immunology t cell b cell type 1 diabetes
Novel Type of Immune Cell Discovered in Type 1 Diabetes Patients
Katarina Zimmer | May 30, 2019 | 6 min read
A rogue hybrid lymphocyte, bearing characteristics of both B and T cells, may play a role in driving autoimmunity in the disease, although the mechanism is far from clear.
Circulating Mitochondrial DNA Alerts Immune System to Danger
Katarina Zimmer | Mar 1, 2018 | 2 min read
In response to short DNA fragments, lymphocytes release mitochondrial DNA that helps trigger an immune response.
Compound Found in Red Wine Boosts Immune Cell Function
Catherine Offord | Oct 16, 2017 | 2 min read
At low doses, resveratrol enhanced human T-cell activity in vitro, while at high doses it interfered with cell signaling. 
Long-Lived Immune Memories
Anna Azvolinsky | Dec 9, 2015 | 3 min read
Two types of memory T cells can preserve immunological memories for more than a decade, a study shows. 
Immune Cells Can Deliver Deadly Packages
Amanda B. Keener | Sep 8, 2015 | 3 min read
Much of the CD4+ T-cell death that occurs during HIV infection may be caused by direct delivery of the virus from neighboring cells, a study shows.
Double-Edged Enzyme
Rina Shaikh-Lesko | Aug 13, 2015 | 3 min read
Researchers find evidence to suggest why an enzyme crucial for fighting off malaria infection is linked to a form of lymphoma.
Mice Cloned From Blood Drops
Chris Palmer | Jun 28, 2013 | 2 min read
Mice have been cloned from single drops of blood taken from their tails using the same technology that produced Dolly the sheep.
Gregory Sonnenberg: Cellular Spy
Dan Cossins | May 1, 2013 | 3 min read
Research Associate, Perelman School of Medicine, University of Pennsylvania. Age: 27
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