iPSCs

The pandemic spurred innovation in a variety of ways, from CRISPR-based diagnostics to cell biology benchwork at home.

The Stanford University professor helped develop a technique to grow brain organoids from induced pluripotent stem cells.

Surgeons will inject approximately 5 million dopamine-producing progenitor cells into patients’ brains.

Cell implants, gene therapy, even optogenetics are making headway in clinical trials to treat various forms of blindness.  

Combining gene editing and stem-cell induction improves efficiency of functional genetic analyses.

Simultaneous exposure to reprogramming and gene-editing plasmids efficiently produces edited pluripotent colonies.

Researchers use an inducible gene to limit tumor growth from human iPSCs transplanted into mice.

Report finds that pathologist involved in anonymous defamation case committed multiple acts of misconduct; growing eggs from stem cells; neutrophils’ role in metastasis; convergent evolution in birds

Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.

Since The Scientist published its first issue in October 1986, life-science research has transformed from a manual and often tedious task to a high-tech, largely automated process of unprecedented efficiency.

Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

Legal expert Henry Greely envisions a world in which advances in biotechnology obviate the need for sexual reproduction as we know it.

The reprogrammed germ-like cells were unable to fertilize eggs, however.