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Molecular Glue ‘Shreds’ Cas9 and Enables a New Form of CRISPR Control
Molecular Glue ‘Shreds’ Cas9 and Enables a New Form of CRISPR Control
In a bid to address safety concerns about immune reactions during treatment with CRISPR-based therapeutics, a new technique speeds up how quickly the body destroys the DNA-cutting enzyme Cas9.
In a bid to address safety concerns about immune reactions during treatment with CRISPR-based therapeutics, a new technique speeds up how quickly the body destroys the DNA-cutting enzyme Cas9.
gene editing
New CRISPR Treatment Could Prevent HIV Reinfection after Viral DNA Excision
Jennifer Zieba, PhD | Aug 21, 2023 | 3 min read
Researchers design dual CRISPR treatments to remove HIV DNA and prevent reinfection in vitro.
The Future of Gene Therapy for a Rare Pediatric Autoimmune Disease
Niki Spahich, PhD | Jul 10, 2023 | 3 min read
By editing a mutated immune regulatory gene in patient cells, Rosa Bacchetta brings hope to those suffering from IPEX syndrome.
Building Bridges for Translational Research - A Special Podcast Series
The Scientist’s Creative Services Team and Cytiva | 2 min read
Translational scientists discuss their experiences taking preclinical concepts to the market.
Chek-Mate for Gliomas
Aparna Nathan, PhD | May 22, 2023 | 3 min read
New research may make immunotherapy possible for hard-to-treat brain tumors.
Viral Vector Platforms for Gene Therapy
The Scientist’s Creative Services Team | Feb 9, 2023 | 1 min read
In both the laboratory and clinic, scientists harness viral genetic transfer capabilities to develop gene therapies that modulate cellular function.
Solutions for mRNA Direct Sequence Mapping
Thermo Fisher Scientific | 1 min read
As mRNA therapeutics gain popularity, a novel solution for their development emerges.
Double Agents: Engineered Bacteria Tackle Pathogenic Biofilms in Mice
Katherine Irving | Jan 26, 2023 | 3 min read
Mycoplasma pneumoniae with pathogenic genes replaced by biofilm-degrading ones enhance survival in a mouse model of ventilator-associated pneumonia.
Can “Gene Writing” Deliver What Gene Editing Can’t?
Dan Robitzski | Dec 12, 2022 | 10+ min read
A biotech startup called Tessera Therapeutics has made a splash with its claims about the trademarked technology. Is the excitement justified?
Focus on Innovation: Scientific Advances Driving Biopharma Market Trends
The Scientist’s Creative Services Team and Tecan | 1 min read
Explore the future of biopharma research and development.
Novel Yeast-Assembly Technique Yields Living Materials
Natalia Mesa, PhD | Nov 23, 2022 | 3 min read
Researchers say structures made of the cells could potentially be used to clean up uranium from oceans, heal wounds, and more.
Skin Bacteria May Trigger Lupus: Mouse Study
Natalia Mesa, PhD | Oct 28, 2022 | 3 min read
Staphylococcus aureus appears to be the culprit.
The Past, Present, and Future of Cell and Gene Therapy
The Scientist’s Creative Services Team and Bio-Rad Laboratories | 1 min read
Embark on the journey of cell and gene therapy—from its conception and development, to its present state, and into its future.
Researchers Fuse Mouse Chromosomes in Scientific First
Natalia Mesa, PhD | Aug 25, 2022 | 4 min read
The findings will likely help elucidate the effects of chromosome fusions, which can cause disease but have also contributed to evolution.
First Person Dosed in Novel Gene Editing Clinical Trial
Amanda Heidt | Jul 12, 2022 | 4 min read
The biotech company Verve Therapeutics launched the study with the aim of using base editing to treat a genetic condition that causes high cholesterol and increases a person's risk of developing cardiovascular disease.
Combinatorial Single Cell CRISPR Screens: Challenges and Applications
The Scientist Creative Services Team in collaboration with 10x Genomics | 2 min read
An expert panel will discuss how single cell sequencing enhances throughput in CRISPR gene editing applications.
New CRISPR Technique Causes Few Unintended Mutations in Fruit Flies
Jason P. Dinh | Jul 1, 2022 | 4 min read
A study finds that CRISPR-Nickase, which changes just one allele of a given gene, improves gene editing efficiency compared with CRISPR-Cas9.
Ten Years of CRISPR
Sophie Fessl, PhD | Jun 28, 2022 | 7 min read
This month marks ten years since CRISPR-Cas9 was repurposed as a gene editing system, so we’re looking back at what has been accomplished in a decade of CRISPR editing.
Technique Talk: CRISPR for Genome Engineering in Drosophila
The Scientist’s Creative Services Team | 1 min read
Discover how CRISPR is revolutionizing gene editing in a classic genetics research model.
Infographic: Two Guide RNAs Make for Large, Stable Insertions
Dan Robitzski | Jun 13, 2022 | 1 min read
A new technique goes beyond CRISPR and writes two complementary strands of DNA directly into the genome.