Deanna MacNeil, PhD Author Profile | The Scientist Magazine®

Infographic showing how CITE-seq detects protein and gene expression in the same cell

Infographic: Capturing a More Complete Picture of Expression

Deanna MacNeil, PhD | Jun 1, 2023 | 1 min read

CITE-seq draws upon the unbiased nature of single-cell RNA sequencing to gather new insights about protein and gene expression within the same cell.

3D image of a neuron cell network with a red glow representing inflammation.

New Insight into Brain Inflammation Inspires New Hope for Epilepsy Treatment

Deanna MacNeil, PhD | Jun 1, 2023 | 2 min read

Clinicians and researchers teamed up to investigate how inappropriate proinflammatory mechanisms contribute to the pathogenesis of drug-refractory epilepsy.

3D rendered illustration of a coronavirus with an overlaid network of lines and dots.

Connecting the Dots That Link Diabetes and Infection Severity

Deanna MacNeil, PhD | May 22, 2023 | 4 min read

Researchers shed light on the immunometabolism of respiratory infection, providing an avenue towards safer COVID-19 therapeutics for those affected by metabolic disorders.

Targeting a Genetic Accident to Treat Disease

Deanna MacNeil, PhD | May 9, 2023 | 2 min read

David Liu shares how integrating chemistry and evolution in his research has directed his work on base editing techniques aimed at developing new therapeutics.

Medical illustration of a scientist replacing part of a DNA molecule with tweezers, representing genome editing.

On the Hunt for the Next Breakthrough in Motor Neuron Disease

Deanna MacNeil, PhD | May 9, 2023 | 3 min read

Researchers leave no stone unturned in the search for a spinal muscular atrophy treatment strategy that uses base editing.

Fluorescence microscopy photograph of human skin depicting stained fibroblasts, key cells involved in wound healing.

Mimicking Tissue Mechanics for Better Wound Healing Models

Deanna MacNeil, PhD | Mar 24, 2023 | 3 min read

Using a 3D culture system that imitates fatty tissue, researchers developed a simpler process to study mesenchymal stem cell aging and tissue regeneration.

Healthcare and medicine, Doctor touch and diagnose a virtual Human Lungs with Covid-19 or coronavirus spread inside on modern interface screen on laboratory, Innovation and Medical technology.

Uncovering Rare Disease Genetic Pathways with Global Biobanks

Deanna MacNeil, PhD | Mar 20, 2023 | 3 min read

Researchers discover new idiopathic pulmonary fibrosis risk factors with multi-ancestry analyses that increase representation of understudied populations.

Context Is Key: Unlocking Tissue Complexity with Spatial Biology

Deanna MacNeil, PhD | Mar 13, 2023 | 4 min read

Scientists combine spatially resolved imaging analyses with cutting edge single cell techniques for greater insight into fundamental and disease relevant pathways.

Researchers engineer a protease-mediated post-translational path faster than gene switches for processes that need to happen quickly, such as insulin release.

Post-Translational Control: The Next Step in Synthetic Circuits

Deanna MacNeil, PhD | Feb 27, 2023 | 3 min read

Researchers engineer a protease-mediated post-translational path faster than gene switches for processes that need to happen quickly, such as insulin release.

A 3D medical illustration of a human heart with a cardiogram in the foreground and a blue background that includes DNA helices.

Connecting the Complexities of Heart Failure and Aging

Deanna MacNeil, PhD | Feb 13, 2023 | 3 min read

Researchers learned how IGFBP7, a senescence signaling protein and biomarker, promotes cardiac remodeling and cellular aging.