cell line

A previously overlooked enzyme called APOBEC3A is linked to the most prevalent mutational signatures in cancer cell lines, a study finds.

Attorneys for the family seek compensation for the company’s sale of cells cloned from tissue removed without consent by doctors at Johns Hopkins Hospital 70 years ago.

The move reflects scientists using more cell lines and organoids in genetic research, although some experts disagree with the decision to scale back the use of animal models.

This could account for some reproducibility problems in cell line research, according to the authors of a comprehensive analysis of HeLa variants.

Authors of a new paper take issue with revisions to regulations on biospecimen research enacted last month, and argue that cell lines should be treated differently from other biospecimens.

An open-source microscopy method can super-resolve live cells even under low lighting.

The Catholic University of America professor was also known for his summer workshops on the latest techniques.

Leonard Freedman, president of the Global Biological Standards Institute, discusses the causes of irreproducible science and his latest effort to spread best practices.

An analysis of contaminated literature finds that tens of thousands of papers used cell lines of questionable origins—and these were in turn cited by hundreds of thousands of other papers.

Researchers continue to identify new T-cell subtypes—and devise ways to use them to fight cancer. The Scientist attempts to catalog them all.

Researchers describe hundreds of induced pluripotent stem cell lines from healthy individuals. 

A screen of human embryonic stem cell lines finds several that accumulated changes in the gene TP53, including aberrations commonly seen in cancer.

Family members of Lacks, the donor behind the widely used HeLa cell line, are planning to sue Johns Hopkins University.

A commercially available glioblastoma cell line appears to be from a different source than its stated origins.

Despite known problems with contamination and mislabeled cell lines, most researchers continue to operate without authenticating cells’ identity.

From tossing out cross-contaminated cell lines to flagging genomic misnomers, a push is on to tidy up biomedical research.

More than 50 years after cross-contamination of cultured cell lines was recognized, the problem continues to plague the scientific community.