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Turning Toxoplasma Against Cancer
Turning Toxoplasma Against Cancer
Several research groups have found that Toxoplasma gondii infection can ramp up antitumor immune responses in mice. Can the single-cell parasite be used to develop safe treatments for humans?
Several research groups have found that Toxoplasma gondii infection can ramp up antitumor immune responses in mice. Can the single-cell parasite be used to develop safe treatments for humans?
cancer therapeutics
Over-the-Counter Antihistamines Could Help Against Cancer
Alejandra Manjarrez, PhD | Nov 24, 2021 | 3 min read
The binding of histamine with one of its receptors within the tumor environment makes cancer cells more resistant to immunotherapy, according to a new study. Blocking that binding could improve responses to treatment.
Cell Diversity Could Spell Trouble for Animal Models of Cancer
David Adam | Nov 19, 2021 | 3 min read
Tracking human cancers in mice shows some unexpected cell changes that could undermine translational research.
Surveillance Gaps: How Cancer Arises
The Scientist’s Creative Services Team | 1 min read
Surveillance Gaps: How Cancer Arises
Sound Waves Aid Brain Tumor Treatment
Ruth Williams | Oct 13, 2021 | 3 min read
In a small clinical study, focusing ultrasound beams on tumors in patients’ brains helped open the blood-brain barrier to facilitate drug delivery.
Gut Fungi Hamper Radiation Therapy in Mice with Cancer
Rachael Moeller Gorman | Aug 11, 2021 | 3 min read
Depleting intestinal fungi allows radiation to effectively fight cancer, likely because the microbes influence the antitumor immune response.
Perfecting Dose Response Assays
The Scientist’s Creative Services Team | 1 min read
Jeffrey Weidner and Eric Niederkofler will discuss strategies for optimizing dose response assays.
p53 Unleashes Endogenous Retroviruses to Tackle Tumors: Study
Marcus A. Banks | Jul 29, 2021 | 4 min read
New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.
José Baselga, Renowned Oncologist, Dies at 61
Asher Jones | Mar 22, 2021 | 2 min read
The cancer researcher and executive vice president of AstraZeneca’s oncology research and development is well known for his role in the development of pivotal breast cancer therapies.
Blocking Cancer Progression and Shrinking Tumors with Antibody-ligand Traps
The Scientist’s Creative Services Team | 1 min read
LuZhe Sun will discuss TGFβ signaling during cancer progression and how researchers can target this pathway.
Bispecific Antibodies Treat Cancer in Mouse Models
Abby Olena, PhD | Mar 5, 2021 | 4 min read
A trio of papers shows that specialized antibodies can direct T cells to destroy cells that display portions of mutant cancer-related proteins, as well as T cells that have become cancerous themselves.
Infographic: Exercise’s Anticancer Mechanisms
Bente Klarlund Pedersen | Apr 1, 2020 | 2 min read
A look at the molecular processes that may feed into the tumor-fighting effects of physical activity
The Structure and Functions of the p53 Pathway: Information Acquisition, Redundancy, and Connectivity
The Scientist’s Creative Services Team | 1 min read
Arnold Levine will discuss his discovery of p53 and the evolution of the field since then, and Jon Chen will discuss the use of single-cell phosphoproteomics in identifying changes in key signaling networks, including p53.
CRISPR Quashes Cancer in Mice
Rachael Moeller Gorman | Apr 1, 2020 | 3 min read
Gene editing can knock out genes crucial to cervical tumor cells’ survival, researchers report.
Regular Exercise Helps Patients Combat Cancer
Bente Klarlund Pedersen | Apr 1, 2020 | 10 min read
Studies point to a role for physical activity in fighting malignancies, improving treatment outcomes, and fostering overall health in patients.
Infographic: CRISPR’d Cancer
Rachael Moeller Gorman | Apr 1, 2020 | 1 min read
Researchers use a new way to deliver CRISPR/Cas9 to tumors in mice, wiping out the cancer.
Glioblastoma on a Chip
Jef Akst | Jul 15, 2019 | 3 min read
Researchers use 3-D printing technology to construct a brain cancer model that accurately recapitulated in vivo biology and predicted patient drug responses.
Infographic: A 3-D Printed Brain Tumor
Jef Akst | Jul 15, 2019 | 1 min read
How researchers create a glioblastoma on a chip that can predict patients’ response to treatments
Scientists Take Aim at Disease-Causing RNAs Using Small-Molecule Drugs
Claire Asher | Apr 1, 2019 | 9 min read
Renewed interest from the biotech industry sparks hope for drugging the nucleic acid to treat cancer and other conditions.
Traitorous Tumor Cells Kill Their Own Kind
Ruth Williams | Jul 11, 2018 | 3 min read
Researchers plan to turn cancer cells into defectors, engineering them to kill the tumors from whence they came, and have tested the approach in mice.